Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used to manage type 2 diabetes and to help with weight loss in patients with obesity. It is chosen because of its efficacy in improving glycemic control, promoting weight loss, and having a relatively minimal risk of causing hypoglycemia compared to other antidiabetic medications.
Compared to other GLP-1 receptor agonists, semaglutide has shown superior efficacy in glycemic control and weight loss. Its long-acting formulation allows for once-weekly dosing, providing greater convenience for patients.
Semaglutide works by mimicking the effects of the naturally occurring hormone GLP-1. It increases insulin secretion, decreases glucagon secretion, and slows gastric emptying, helping to lower blood sugar levels and promote weight loss.
Semaglutide is administered as a subcutaneous injection. It is typically injected once a week, on the same day each week, using a prefilled pen. The injection can be given at any time of the day, with or without meals.
Semaglutide has been shown to promote significant weight loss in patients with obesity and those with type 2 diabetes. Studies have demonstrated an average weight loss of around 5-10% of the initial body weight, with some patients experiencing even greater weight loss. Weight loss is primarily due to reduced appetite and increased satiety, leading to decreased caloric intake.
Some common side effects of semaglutide include:
Rare but serious side effects may include:
To manage side effects from semaglutide, consider the following functional medicine approaches:
Always consult with your healthcare provider before making any changes to your treatment plan or incorporating supplements to manage side effects. They can provide personalized recommendations based on your specific medical history and needs.
At Patients Medical, our goal is to offer a variety of programs and treatments that can help you lose weight quickly and safely. Our physicians will create a customized plan for you that may include a combination of prescription, conventional and holistic medicine, and recommend dietary and lifestyle changes.