Semaglutide

Why Semaglutide?

Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used to manage type 2 diabetes and to help with weight loss in patients with obesity. It is chosen because of its efficacy in improving glycemic control, promoting weight loss, and having a relatively minimal risk of causing hypoglycemia compared to other antidiabetic medications.

Semaglutide versus other GLP-1 medications:

Compared to other GLP-1 receptor agonists, semaglutide has shown superior efficacy in glycemic control and weight loss. Its long-acting formulation allows for once-weekly dosing, providing greater convenience for patients.

How Semaglutide works:

Semaglutide works by mimicking the effects of the naturally occurring hormone GLP-1. It increases insulin secretion, decreases glucagon secretion, and slows gastric emptying, helping to lower blood sugar levels and promote weight loss.

How to take Semaglutide:

Semaglutide is administered as a subcutaneous injection. It is typically injected once a week, on the same day each week, using a prefilled pen. The injection can be given at any time of the day, with or without meals.

Weekly dosing schedule:

First four weeks: Start with a dose of 0.25 mg once a week.
Second four weeks: Increase the dose to 0.5 mg once a week.
Third four weeks: The dose can be further increased to 1.0 mg once a week if needed.
Fourth week and continuing dosage: The maximum dose of semaglutide is 2.4 mg once a week for weight management and 1.0 mg once a week for type 2 diabetes management.

Weight loss benefits by taking Semaglutide:

Semaglutide has been shown to promote significant weight loss in patients with obesity and those with type 2 diabetes. Studies have demonstrated an average weight loss of around 5-10% of the initial body weight, with some patients experiencing even greater weight loss. Weight loss is primarily due to reduced appetite and increased satiety, leading to decreased caloric intake.

How often should you do a blood draw for testing for side effects? Every four weeks?

The frequency of blood tests while taking semaglutide will depend on the individual and their specific medical condition. It is recommended to monitor blood sugar levels and kidney function regularly, especially during the initial weeks of therapy. Your healthcare provider will determine the appropriate testing frequency based on your medical history and response to the medication.

Side effects by taking Semaglutide:

Some common side effects of semaglutide include:

Rare but serious side effects may include:

How to address the Semaglutide side effects using functional medicine support, including supplements and IV Drips:

To manage side effects from semaglutide, consider the following functional medicine approaches:

Hydration: Ensuring adequate fluid intake can help alleviate gastrointestinal side effects like nausea, vomiting, and diarrhea.
Ginger: Ginger supplements or tea may help reduce nausea.
Probiotics: Probiotic supplements can help restore gut balance and alleviate gastrointestinal side effects.

Slow dose escalation: Gradually increasing the dose of semaglutide, as recommended by your healthcare provider, can help reduce the severity of side effects as the body adjusts to the medication.
Dietary adjustments: Eating smaller, more frequent meals and avoiding high-fat or spicy foods can help manage gastrointestinal side effects.
Electrolyte supplementation: Replenishing electrolytes, particularly if experiencing diarrhea or vomiting, can help maintain proper electrolyte balance.
Vitamin and mineral supplementation: Some individuals may benefit from vitamin and mineral supplementation to ensure adequate nutrient intake, especially if appetite is reduced.
Stress management: Engaging in stress-reducing activities such as meditation, deep breathing exercises, or yoga can help manage stress, which may exacerbate side effects.
Sleep optimization: Prioritizing sleep and establishing a healthy sleep routine can help promote overall well-being and potentially reduce side effects.
IV Drips: In some cases, IV therapy may be used to replenish fluids, electrolytes, and essential nutrients lost due to gastrointestinal side effects. Consult with a healthcare professional before considering IV therapy.

Always consult with your healthcare provider before making any changes to your treatment plan or incorporating supplements to manage side effects. They can provide personalized recommendations based on your specific medical history and needs.

READY TO LOSE WEIGHT?

At Patients Medical, our goal is to offer a variety of programs and treatments that can help you lose weight quickly and safely. Our physicians will create a customized plan for you that may include a combination of prescription, conventional and holistic medicine, and recommend dietary and lifestyle changes.